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诺诚健华：2025年股东周年大会会议资料 （下载公告）
公告日期:2025-04-29

InnoCare Pharma

(1) 2024

(2) 2024

(3) 2024

(4)

(5)(6)(7)(8)

(9)202562088AGM-1AGM-8

( www.hkexnews.hk )( www.innocarepharma.com )

482025618

17M

2025428

– i –

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 5

1.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6

2.2024 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6

3.2024 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 6

4.2024 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7

5.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 7

6. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8

7. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 9

8. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

9.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

10.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 10

11. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

12.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 20

13. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

14.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 21

15. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

16. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 22

— 2024 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . I-1

– ii –

— . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . II-1

— . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . III-1

. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AGM-1

202420241231202420241231

2025620

AGM-1AGM-8

20151139969688428

7%

93%7%

0.000002

III-2

2025424

2020323

202013

a.b.

c.

0.000002

0.000002

1.01

%

??

– 5 –

InnoCare Pharma

Ogier Global (Cayman) Limited89 Nexus Way, Camana BayGrand Cayman, KY1-9009Cayman Islands

(1) 2024

(2) 2024

(3) 2024

(4)

(5)(6)(7)(8)

(9)

1.

AGM-1AGM-8

(1) 2024(2)2024(3)2024(4)

(5)(6)2025

(7)(8)

2. 2024

202420242025328(http://www.sse.com.cn)(http://www.hkexnews.hk)(www.innocarepharma.com)

20242025428(http://www.hkexnews.hk)(http://www.sse.com.cn)(www.innocarepharma.com)

3. 2024

2024

4. 2024

2024

202420253272024

5.

20%

1,762,567,2021,686,000

352,176,2407

520%

10%

1,494,598,235

266,282,9677149,459,82326,628,296

6.

114.(a)

20251212024925

7.

(a)

(b) 3.13

(c)

3.13

8.

9.

10.

( http://www.hkexnews.hk )2021632022518202266

( http://www.hkexnews.hk )202131120215262021913202241320225112022612022852022822202291202298

( http://www.hkexnews.hk )( http://www.sse.com.cn )

202291620229202025327

2022715[2022]1524

A264,648,217

11.03

2,919.07140.25

2,778.82

2022916[2022]61576403_B01

202532720241231202412311,428.24

1,350.5820241231

20241231

1,494,220.61,494,220.61,085,626.7

116,146.6116,146.621,890.1273,851.4273,851.4113,023.460,952.360,952.328,859.5833,644.7833,644.7101,178.6

2,778,815.62,778,815.61,350,578.3

1.

ICP-19221,285.727,485.72ICP-0336,078.66

2,078.66ICP-B034,862.930

20,841.114,841.11ICP-B794

10,000.0028,662.93

1ICP-022412,306.6—412,306.62ICP-192212,857.2-138,000.074,857.23ICP-723125,046.7—125,046.74ICP-33269,470.4—69,470.45ICP-03360,786.6-40,000.020,786.66ICP-18957,313.1—57,313.17ICP-488154,918.9—154,918.98ICP-49057,868.8—57,868.89ICP-24857,313.1—57,313.110ICP-B0348,629.3-48,629.30.011ICP-B794—100,000.0100,000.0

—286,629.3286,629.313208,411.1-160,000.048,411.11429,298.8—29,298.8

1,494,220.6—1,494,220.6

2.

2,142.471,342.471,675.842,475.84

116,758.48000.024,758.4272,808.6—72,808.6321,424.7-8000.013,424.742,877.5—2,877.552,277.4—2,277.4

116,146.6—116,146.6

3.

3,882.641,082.645,254.38

8,054.38

138,826.4-28,000.010,826.4252,543.828,000.080,543.83177,111.6—177,111.645,369.6—5,369.6

273,851.4—273,851.4

4.

1,245.4402,432.16

3,077.6

274.55874.55

112,454.4-12,454.40.0242,814.6—42,814.6

2.118,493.0—18,493.0

2.224,321.66,454.430,776.032,745.56,000.08,745.542,501.0—2,501.05436.8—

436.8

60,952.3—60,952.3

1.

ICP-B794

(ADC)B7-H3ADCICP-B794

B7-H3ICP-B7942025ICP-B794INDICP-B794

ICP-192ICP-033ICP-B03

ICP-192ICP-033ICP-B03

2.

3.

2.0

(CLL)(SLL)(r/r CLL/SLL)(MCL)(r/r MCL)(MZL)(r/r MZL)

MZLBTK2024

?

1049.14%10

tafasitamab

4.

—

2025327A

—

—

11.

20256172025620

2025616183171712–1716

12.

AGM-1AGM-8

(i)(ii)(iii)

13.

( www.hkexnews.hk )( www.innocarepharma.com )

482025618

14.

15.

16.

(1)2024(2)2024

(3)2024(4)(5)

(6)2025(7)(8)

2025428

2024

– I-1 –

2024

2024

—

2024

2024

2024?

TafasitamabBLA13I/II/III

2.0

2024

– I-2 –

2024

202412

12024.03.281722024.03.28132024.04.22242024.05.13152024.05.30262024.06.25372024.07.17182024.08.20392024.09.253102024.11.112112024.11.265122024.12.171

2024

– I-3 –

1 A

277,881.5620242023

2024

—

— A

2024

– I-4 –

—

AA

e

2024

– I-5 –

20242

2024

20245

20246

20242

2024

– I-6 –

20252025

—

2025327

– II-1 –

13.51(2)

Ph.D.61201511320168182019927

20199610201010MerckCo

2011820158PPD

?

BioDuro LLC(Sino-American Pharmaceutical Association)1750NatureBloodProceedings of the National Academy of SciencesJournal of BiologicalChemistryTransgenic mice expressingAPC resistance Factor Vcloning and expression of dog gonadotropin releasing hormone receptorDNA encoding monkey gonadotropin releasing hormone receptor

19837199212(Purdue University)19969

(The Howard Hughes Medical Institute)

202013

XV103,118,916

– II-2 –

Ph.D.5620151132019927

20028200812

20103Shenzhou Tianchen TechnologyInc.20116201332013720158

20158201841991719995

(Johns Hopkins University)

202013

XV117,439,593

3920213311020082011

2011120157Oriza Cowin2015

2016202020191128

6885782020819

– II-3 –

09926202091802171

2021331

XV

532020311

1875200872018620027

1994720026Arthur Andersen1994720052

(University of Buffalo, the State University of New York)19973CICPA

2020311

30,000XV

– II-4 –

61202381992520079(University of Michigan)20071020236(University of California San Diego)2013

MEK1/2MEKmTORHippomTORC1TSC1/2-RhebRagAMPKmTORC1ULK1VPS34mTORC1mTOR

HippoHippoHippo

15H179

19826198912

19891219919

2025121

30,000

XV

– II-5 –

3.13

(i)(ii)(iii)

13.51(2)(h)(v)

– III-1 –

10%10%

(i)(ii)12(iii)(iv)

(v)

1,496,284,235266,282,9671,686,000

10%

149,459,823

– III-2 –

26,628,29610%

20241231

– III-3 –

(i)

(ii)

(iii)

– III-4 –

HHLR Advisors, Ltd.208,671,22211.83%HHLRAdvisors, Ltd.13.15%

– III-5 –

202511,126,0005.825.576,421,700202412560,0006.125.863,340,550

1,686,0009,762,250

– III-6 –

2024

45.064.03

55.384.22

64.924.31

75.154.31

85.124.38

96.964.87

107.786.20

117.926.04

127.035.802025

16.125.02

210.025.34

310.208.15

410.966.89

– AGM-1 –

InnoCare Pharma

2025620

1. 20241231

2. 2024

3. 2024

4. 20245.

(i) (iii)

(v)

– AGM-2 –

2024611

(ii) (i)

(iii) (i)

(1) (v)(2)

(3)

(4)

20%

– AGM-3 –

(i)

(v)(ii)

(iv)

(v)

(a) (1)

(2)

(i)(ii)

(iii)

(b)

(1)(2)

(3)

– AGM-4 –

(c)

6.

(i) (ii)(iv)

– AGM-5 –

(ii) (i)

10%

(iii) (i)

10%

(iv) (i)(ii)(iii)(i)(ii)(iii)

(v)

(a)(b)

(c)

(d) 12(e)

– AGM-6 –

7.

2024611

10%10%8.9.10.11.12.13.14.

15.

– AGM-7 –

16.

2025428

(i) 567(ii)(iii)

(iv)

4820256

18317M

(v) 202561720256

2025616

171712–1716(vi) 813

2025428(vii) 5

– AGM-8 –

(viii) 6

2025428

(ix)(x) 2025428
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